This trial aims to evaluate a new contact lens system to culture and transfer limbal stem cells to the corneal surface in patients with limbal stem cell deficiency. The trial is being conducted by the the School of Medical Sciences at the University of New South Wales. Limbal stem cells will be harvested from the patient unaffected eye and will then be cultured on specially designed contact lens, before being transferred to the patient's cornea. Participants will be monitored for complications and assessed for changes in their clinical condition, including examination of ocular health and corneal epithelium integrity. The trial started in May 2007 and expects to recruit 30 patients with limbal stem cell deficiency.