CTRI/2012/04/002560

This trial aims to assess the safety and effectiveness of donatd mesenchymal stem cells in patients with alcoholic liver cirrhosis. The trial is being conducted in 10 different centres throughout India in conjunction with Stempeutics Research Pvt. Ltd. The trial seeks to recruit 60 subjects by April 2014 with moderate to severe alcoholic liver cirrhosis. The participants will be randomised into three groups, each receiving a proprietary, donated mesenchymal stem cell preparation in either a low, intermediate or high dose. The stem cells will be injected directly into the hepatic artery with a catheter inserted through a percutaneous puncture of the femoral artery. Participants will be monitored for complications and assessed for liver function.