CTRI/2012/05/002638

This pilot clinical study is investigating the efficacy of the patient's own stem cells in repairing damaged growth plate of long bones in children. The small trial is being conducted by the Christian Medical College Vellore in Tamil Nadu and proposes to enrol five children who have sustained permanent damage to the epiphyseal growth plate of a long bone. Bone marrow stem cells will be harvested from the participant's hip (iliac crest), expanded in a laboratory and surgically implanted into the growth plate after the scar tissue has been removed. Bone growth will be measured at three monthly intervals for 2 years. The study commenced in March 2012 and is expected to run to March 2014.