Crohn's Disease

Stem cells from bone marrow are being investigated as possible treatments for Crohns Disease. Click on the link provided to find out more about each trial. It remains too early to know which approach will be most suitable. We need evidence collected in clinical trials to determine if a proposed stem cell treatment is both safe and effective.

tagged as Crohn's Disease

  • A Single Centre Phase II Study Of Haematopoietic Stem Cell Transplantation for Severe Auto-Immune Diseases Location: Australia
    Overview: This trial is evaluating the use of combining immunosuppression and the patient's bone marrow stem cells in patients with serious diseases of the immune system which have not responded to conventional treatments. The trial is being conducted at St Vincent's Hospital in Sydney and began recruiting patients in March 2011 with plans to recruit 30 subjects by December 2015. The conditions being investigated in the trial include Scleroderma, Multiple Sclerosis, Systemic Lupus Erythematosus (SLE), vasculitis, Crohn's disease and Behcet's disease. Participants will be given Granulocyte Colony Stimulating Factor (G-CSF) to stimulate the bone marrow into releasing stem cells, which will then be harvested from the blood of each participant. The patients will then undergo a course of intensive chemotherapy and/or immunotherapy depending on the individual condition after which they will receive an infusion of their own stem cells. Participants will be monitored for complications and assessed for changes in their clinical condition.
    Link to Clinical Registry
    Trial Design: Observational Study
    Status: Open - Recruiting
    Stem Cell: Adult Bone Marrow Stem Cells