Type 1 Diabetes

Stem cells from bone marrow and placental tissue are being investigated as possible treatments for diabetes. Click on the link provided to find out more about each trial. It remains too early to know which approach will be most suitable. We need evidence collected in clinical trials to determine if a proposed stem cell treatment is both safe and effective.

tagged as Type 1 Diabetes

  • Islet Transplantation in Patients With "Brittle" Type I Diabetes Location: US
    Overview: This trial aims to investigate the effectiveness of infusing donated pancreatic islet stem cells directly into the liver and pancreas of patients with type 1 diabetes. The trial is being conducted at the University of Chicago Medical Centre and proposes to enrol 10 patients with type I diabetes who are prone to severe hypoglycaemic events. All the participants will receive a transfusion of a preparation of donated islet stem cells directly into the hepatic venous system via the portal vein. Insulin production will be monitored for one year after the transfusion. The study is expected to be completed by June 2019.
    Link to Clinical Registry
    Trial Design: Safety and Efficacy Study
    Status: Open - Recruiting
    Stem Cell: Stem Cells (unspecified)
  • Investigation on Autologous Mesenchymal Stem Cell Transplantation in Diabetic Retinopathy Location: Iran
    Overview: This trial aims to investigate the effect of patient's own bone marrow stem cells in the treatment of retinopathy due to type 1 diabetes. The trial being conducted by the Teheran University of Medical Sciences and expects to enrol 20 patients by end 2013. All participants will have stem cells harvested from their bone marrow and expanded in the laboratory before being intravenously (IV) transfused into the participants. Participants will be monitored for complications and improvements in their condition.
    Link to Clinical Registry
    Trial Design: Safety and Efficacy Study
    Status: Open - Recruiting
    Stem Cell: Adult Bone Marrow Stem Cells