Heart Failure

Stem cells from bone marrow are being investigated as possible treatments for heart failure. Click on the link provided to find out more about each trial. It remains too early to know which approach will be most suitable. We need evidence collected in clinical trials to determine if a proposed stem cell treatment is both safe and effective.

tagged as Heart Failure

  • Autologous Bone Marrow Stem Cells in Patients with Heart Failure Location: China
    Overview: This trial is investigating the therapeutic effect of the patient's own bone marrow stem cells in the treatment of chronic heart failure. The trial is being conducted at the 105th PLA Hospital in Anhui Province and aims to enrol 100 subjects with significant heart failure. The participants will be given an intravenous (IV) infusion of stem cells that have been previously harvested from their own bone marrow and expanded in the laboratory. Changes in cardiac function will be monitored by using standard tests. The study commenced in July 2012. No end date has been provided.
    Link to Clinical Registry
    Trial Design: Safety and Efficacy Study
    Status: Open - Recruiting
    Stem Cell: Adult Bone Marrow Stem Cells
  • Randomized Clinical Trial of Intravenous Infusion Umbilical Cord Mesenchymal Stem Cells on Cardiopathy (RIMECARD) Location: Chile
    Overview: This trial aims to evaluate the use of stem cells from umbilical cord in the treatment of heart failure. The trial is being conducted at the Universidad de los Andes in Santiago and proposes to recruit 30 patients between December 2012 and January 2014. The participants will have their cardiac function carefully calibrated and recorded three months prior to the commencement of the trial, and be randomly assigned into one of two groups. The experimental group will receive a single intravenous (IV) injection of mesenchymal stem cells that have been obtained from donated cord blood. The control group will receive a placebo intravenous injection. Participants will be monitored for complications and changes in clinical condition at three monthly intervals for one year.
    Link to Clinical Registry
    Trial Design: Safety and Efficacy Study
    Status: Open - Recruiting
    Stem Cell: Umbilical Cord Stem Cells