The trial is being conducted by the National Institute of Health Clinical Centre in Bethesda, Maryland and seeks to investigate the role of the patient’s own stem cells to repair heart damage. Participants will be have their own bone marrow stem cell cells collected about 3 weeks before surgery and then have the cells injected directly into damaged areas of the heart during open-heart surgery.  Participants will be assessed for safety and feasibility of such an injection as well as changes in heart function. The trial expects to recruit 24 subjects between February 2012 and September 2013.