NCT01584986

This trial evaluated the ability of the patient’s own blood vessel forming stem cells (angiogenic cell precursors – ACPs) to regenerate arteries in patients with peripheral arterial disease. The study was conducted by the Semmelweis University Department of Cardiovascular Surgery and the Kelen Hospital in Budapest in conjunction with TheraVitae Ltd. Participants in the study were at high risk of amputation of the affected limb and enrolled into the control or treatment arms of the study. Those in the control arm received only conventional treatment. Those in the treatment arm received into the muscles of the affected limb. All participants were monitored for changes in vascular function. The trial recruited 22 patients between May 2008 and April 2009 and was completed in July 2009. It is not clear whether the results of this study have been published.