NCT01649648

This study aims to investigate the safety, feasibility and effectiveness of collecting and infusing a baby's own umbilical cord blood after brain injury. The trial is being conducted by the National University Hospital in Singapore and the National Medical Research Council (NMRC). The trial expects to enrol 10, full-term infants that have developed hypoxic ischaemic encephalopathy during and shortly after birth. The umbilical cord blood of all infants born at the participating institutions will be kept fresh (refrigerated but not frozen) for three days after birth. In that time any infant showing evidence of hypoxic ischaemic encephalopathy will be given an intravenous infusion of its own umbilical cord blood. The children will be monitored for complications and changes in their clinical condition. The trial commenced in September 2011 and is expected to run until September 2015.