The aim of this trial is to evaluate the safety and effectiveness of transplanting stem cells in patients with severe heart failure due to chronic ischemic cardiomyopathy. The trial is being conducted by the Kyoto Prefecture University of Medicine, the Asahikawa Medical College and the National Cerebral and Cardiovascular Centre Translation Research Informatics Centre in Kobe. The cells used in the trial have been obtained from donated bone marrow mesenchymal stem cells and have been able to grow into heart stem cells in the laboratory (also referred to as Cardiac Stem Cell progenitor cells). Participants in this study will receive an infusion of the hCSC stem cells into a major heart artery, as well as a growth factor directly into the heart muscle around known infarcted areas. Participants will be monitored for complications and changes in their condition. The trial aims to recruit six patients by end 2013.