Autism

Stem cells from cord blood and bone marrow are being investigated as possible treatments for autism. Click on the link provided to find out more about each trial. It remains too early to know which approach will be most suitable, or even provide any benefit. We need evidence collected in clinical trials to determine if a proposed stem cell treatment is both safe and effective.

tagged as Autism

  • Autologous Cord Blood Stem Cells for Autism Location: US
    Overview: This trial aims is to determine the effect of umbilical cord blood infusion in treating children with autism. The trial is being undertaken by the Sutter Institute for Medical Research in Sacramento California and expects to recruit 30 children from 2 to 7 years of age that have been diagnosed with autism. Participants will be randomly divided into two groups. One group will receive an infusion of their own umbilical cord blood (initial experimental group). The other group will receive a placebo infusion of saline, but then after 24 weeks, they will receive their own umbilical cord blood. The initial experimental group will receive a placebo injection at 24 weeks. Both groups will be tested at 24 weeks after initial infusion, and then again after another 24 weeks. The participants, their carers and their doctors will not know which group they have been assigned to. In the follow-up period each child will be monitored for complications and changes in their clinical condition. The trial commenced in August 2012 and is expected to conclude in August 2013.
    Link to Clinical Registry
    Trial Design: Safety and Efficacy Study
    Status: Open - Recruiting
    Stem Cell: Umbilical Cord Stem Cells
  • Autologous Bone Marrow Stem Cells for Children With Autism Spectrum Disorders Location: Mexico
    Overview: This trial aims to investigate the effects of a single injection of stem cells from the bone marrow in children with diagnosed Autism. The trial is being conducted by the Hospital Universario in Monterrey and proposes to enrol 30 subjects between November 2012 and November 2013. All participants will receive an injection of G-CSF to release stem cells from the bone marrow into the circulation. The stem cells will then be collected from the child's blood. Half the participants will injected with the stem cells in the first six months (initial experimental group), while the other half will not have the cells injected until the stage of the second six months (initially a control group). The cells will be injected into the fluid that surrounds the spinal cord (intrathecal injection). Participants will be monitored for complications following the injection and changes in clinical condition.
    Link to Clinical Registry
    Trial Design: Safety and Efficacy Study
    Status: Open - Recruiting
    Stem Cell: Adult Bone Marrow Stem Cells