Bone repair

Stem cells from fat and bone marrow are being investigated as possible treatments for bone repair. Click on the link provided to find out more about each trial. It remains too early to know which approach will be most suitable. We need evidence collected in clinical trials to determine if a proposed stem cell treatment is both safe and effective.

tagged as Bone repair

  • Cranial Reconstruction Using Mesenchymal Stromal Cells and Resorbable Biomaterials Location: Australia
    Overview: This pilot study aims to demonstrate the safety and effectiveness of using the patient's own mesenchymal stem cells in cranial reconstruction. The trial being conducted at the Royal Perth Hospital in Western Australia from January 2013 to December 2015 and expects to enrol 10 participants who require cranial reconstruction as a result of surgery or trauma. This trial proposes to use an implant that is customised to match the skull defect and is a sandwich of a scaffold embedded with mesenchymal stem cells that have been harvested from the patient and expanded in the laboratory. It is expected that the stem cells will multiply to occupy the scaffold with bone generating cells, which will eventually replace the entire scaffold with new bone. Participants will be assessed for complications. Bone formation will be monitored by CT scanning.
    Link to Clinical Registry
    Trial Design: Safety and Efficacy Study
    Status: Not yet started
    Stem Cell: Adult Bone Marrow Stem Cells