Muscle & tendon repair

Stem cells from cord blood and bone marrow are being investigated as possible treatments for muscle and tendon repair. Click on the link provided to find out more about each trial. It remains too early to know which approach will be most suitable. We need evidence collected in clinical trials to determine if a proposed stem cell treatment is both safe and effective.

tagged as Muscle & tendon repair

  • Mensenchymal Stem Cell Included in OrthADAPT Membrane for Rotator Cuff Tears Repair Location: Spain
    Overview: This trial aims to determine the benefit of using patient's own bone marrow derived stem cells in repairing torn shoulder rotator cuffs. The trial is being conducted by the Hospital San Carlos in Madrid and expects to enrol 10 subjects by December 2013. Participants, all of who have a severe tear of the supraspinatus tendon, will be randomly divided into two groups. The control group will receive a conventional surgical repair using a collagen type I membrane (orthADAPT product from Penta Biomedical). The experimental group will undergo the same repair except that the collagen membrane will be impregnated with the patient's own bone marrow stem cells. Participants will be monitored for complications and for changes in clinical condition. The clinical and radiological practitioners involved in these assessments will not know what treatment each patients receives.
    Link to Clinical Registry
    Trial Design: Therapeutic intervention
    Status: Open - Recruiting
    Stem Cell: Adult Bone Marrow Stem Cells
  • A Phase 1 Study to Evaluate the Potential Role of Mesenchymal Stem Cells in the Treatment of Chronic Refractory Tendinopathy Location: Australia
    Overview: This trial is investigating the effects of umbilical cord stem cells in treating tendon repair. The study has being conducted by the Mater Medical Research Institute and Mater Health in Brisbane, Queensland and proposes to recruit nine patients with clinically and ultrasound diagnosed Achilles tendonopathy. Participants will be divided into one of three groups each receiving different doses of stem cells injected directly into damaged tendon. The trial partially complete but is currently on hold. Participants will be monitored for complications and assessed for changes in their clinical condition.
    Link to Clinical Registry
    Trial Design: Safety and Efficacy Study
    Status: Open - Recruiting
    Stem Cell: Umbilical Cord Stem Cells