Osteoarthritis

Stem cells from fat and bone marrow are being investigated as possible treatments for Osteoarthritis. Click on the link provided to find out more about each trial. It remains too early to know which approach will be most suitable. We need evidence collected in clinical trials to determine if a proposed stem cell treatment is both safe and effective.

tagged as Osteoarthritis

  • Adipose-Derived Stem Cells in Patients with Knee Osetoarthritis Location: Australia
    Overview: This trial aims to compare the effect of the patient's own fat stem cells in the treatment of osteoarthritis of the knee. The trial is being conducted by the Lakeside Medical Centre in Albert Park and the Australian Catholic University in Melbourne. The trial that has not started yet according to the registration information, but proposes to recruit 60 patients. Participants will be randomly assigned into two different categories. One group will receive an injection of hyaluronic acid derivative (Hylan GF). Another group will receive a suspension of cells derived from liposuction. The information provided on the ANZCTR indicates that the subjects will receive three injections but does not provide further details about the preparation of the cells. Participants will be monitored for complications and assessed for changes in their clinical condition.
    Link to Clinical Registry
    Trial Design: Safety and Efficacy Study
    Status: Not yet started
    Stem Cell: Adult Fatty Tissue Stem Cells
  • Evaluation of mesenchymal stem cells in the treatment of knee osteoarthritis – A randomised Controlled Trial Location: Australia
    Overview: This study seeks to assess the response of osteoarthritis of the knee to different dosing and injection protocols of adipose-derived (liposuction) mesenchymal stem cells collected from the participant (autologous). 40 participants will be enrolled in the Melbourne study and randomly separated into either one of three treatment groups or a control group receiving conservative management. If the treatment groups show significant and conclusive improvements the control group will be offered cross over at 12months. This study is funded and there will be no treatment charge to the participants.
    Link to Clinical Registry
    Trial Design: Safety and Efficacy Study
    Status: Open - Recruiting
    Stem Cell: Adult Fatty Tissue Stem Cells