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Retinitis Pigmentosa

Stem cells from bone marrow are being investigated as possible treatments for Retinitis Pigmentosa. Click on the link provided to find out more about each trial. It remains too early to know which approach will be most suitable. We need evidence collected in clinical trials to determine if a proposed stem cell treatment is both safe and effective.

tagged as Retinitis Pigmentosa

  • Feasibility and Safety of Adult Human Bone Marrow-derived Mesenchymal Stem Cells by Intravitreal Injection in Patients With Retinitis Pigmentosa Location: Thailand
    Overview: This study is investigating whether stem cells from the patient’s own bone marrow could benefit patients with Retinitis Pigmentosa, a condition characterised by loss of vision due to degeneration of cells of the retina (photoreceptors). The study involves cells being injected directly into the eye (intravitreal) and is being conducted by the Mahidol University in Bangkok. Participation is by invitation only with a total of 10 patients enrolled by March 2014. Participants will be monitored for changes in the retina and in vision.
    Link to Clinical Registry
    Trial Design: Safety Study
    Status: Not yet started
    Stem Cell: Adult Bone Marrow Stem Cells
  • Autologous Bone Marrow-Derived Stem Cells Transplantation For Retinitis Pigmentosa Location: Brazil
    Overview: This trial is being conducted by the University of São Paulo and aims to recruit 50 subjects suffering from Retinitis Pigmentosa between June 2011 and June 2013. All participants will receive an injection into their eye of their own bone marrow stem cells. They will be assessed regularly over the next six months and monitored for changes in vision, inflammation and abnormal cell growth such as tumours.
    Link to Clinical Registry
    Trial Design: Safety and Efficacy Study
    Status: Open - Recruiting
    Stem Cell: Adult Bone Marrow Stem Cells
  • Clinical Trial of Autologous Intravitreal Bone Marrow CD34+ Stem Cells for Retinopathy Location: US
    Overview: This pilot clinical trial is designed to evaluate the safety and effectiveness of transplanting bone marrow stem cells into the eyes patient’s with irreversible vision loss from various retinal degenerative conditions including macular degeneration, retinitis pigmentosa, diabetic retinopathy or retinal vein occlusion. The trial is being conducted by the University of California Davis. Participants will receive their own cells, isolated from their bone marrow, directly into the eye (intravitreal injection). Participants will be monitored for complications including infection and tumour growth, as well as structural evidence of successful engraftment and changes to vision. The trial expects to enrol 15 subjects by December 2013.
    Link to Clinical Registry
    Trial Design: Safety and Efficacy Study
    Status: Open - Recruiting
    Stem Cell: Adult Bone Marrow Stem Cells

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