Retinopathy

Stem cells from bone marrow are being investigated as possible treatments for retinpathy. Click on the link provided to find out more about each trial. It remains too early to know which approach will be most suitable. We need evidence collected in clinical trials to determine if a proposed stem cell treatment is both safe and effective.

tagged as Retinopathy

  • Effect of Intravitreal Bone Marrow Stem Cells on Ischemic Retinopathy Location: Brazil
    Overview: This study is being conducted by the University of Sao Paulo to investigate stem cells from bone marrow can improve vision in patients suffering ischaemic retinopathy. Mesenchymal stem cells will be collected from the patient’s own bone marrow and injected directly into the eye. Changes in the thickness of the retina as well as improvements in vision will be measured. The trial commenced in September 2011 and is seeking to enrol 30 patients.
    Link to Clinical Registry
    Trial Design: Safety and Efficacy Study
    Status: Open - Recruiting
    Stem Cell: Adult Bone Marrow Stem Cells
  • Investigation on Autologous Mesenchymal Stem Cell Transplantation in Diabetic Retinopathy Location: Iran
    Overview: This trial aims to investigate the effect of patient's own bone marrow stem cells in the treatment of retinopathy due to type 1 diabetes. The trial being conducted by the Teheran University of Medical Sciences and expects to enrol 20 patients by end 2013. All participants will have stem cells harvested from their bone marrow and expanded in the laboratory before being intravenously (IV) transfused into the participants. Participants will be monitored for complications and improvements in their condition.
    Link to Clinical Registry
    Trial Design: Safety and Efficacy Study
    Status: Open - Recruiting
    Stem Cell: Adult Bone Marrow Stem Cells
  • Clinical Trial of Autologous Intravitreal Bone Marrow CD34+ Stem Cells for Retinopathy Location: US
    Overview: This pilot clinical trial is designed to evaluate the safety and effectiveness of transplanting bone marrow stem cells into the eyes patient’s with irreversible vision loss from various retinal degenerative conditions including macular degeneration, retinitis pigmentosa, diabetic retinopathy or retinal vein occlusion. The trial is being conducted by the University of California Davis. Participants will receive their own cells, isolated from their bone marrow, directly into the eye (intravitreal injection). Participants will be monitored for complications including infection and tumour growth, as well as structural evidence of successful engraftment and changes to vision. The trial expects to enrol 15 subjects by December 2013.
    Link to Clinical Registry
    Trial Design: Safety and Efficacy Study
    Status: Open - Recruiting
    Stem Cell: Adult Bone Marrow Stem Cells