Professor Helen Abud

 - Chief Investigator

Research focus: Stem cells in intestinal disease and bowel cancer

Professor Helen Abud is Head of the Epithelial Regeneration Laboratory and Director of the Monash BDI Organoid Program in the Cancer Program within the Biomedicine Discovery Institute and the Department of Anatomy and Developmental Biology, Monash University. She is also Director of Developmental Biology Education at Monash.
Prof Helen Abud completed her undergraduate degree at Melbourne University, and then trained at the Walter and Eliza Hall Institute before undertaking her doctorate at Oxford University, UK in Cell and Developmental Biology. This was followed by postdoctoral training in the Department of Anatomy (Oxford), Peter MacCallum Cancer Centre (Melbourne) and the Ludwig Institute for Cancer Research (Melbourne). Prof Abud's current research is centred on understanding the molecular mechanisms and environmental influences that regulate stem cells within normal tissues and tumours.  Prof Abud has a particular interest in molecules that promote intestinal epithelial development and regeneration following damage and how these factors may be altered during aging, degenerative diseases and colon cancer.  She collaborates with clinicians at Cabrini Hospital and Monash Health to collect and grow organoids from normal human gastrointestinal epithelium, primary and metastatic tumours.  These organoids are currently being used for a variety of biological studies including response to drug treatments and environment.