Profiles

Dr James Hudson

 - Affiliate Investigator

Research focus: Organoid research specifically for cardiac diseases





Dr Hudson completed a double major in Chemical and Biological Engineering in 2006 at The University of Queensland. He subsequently completed his PhD from The University of Queensland in 2011 in directed differentiation of stem cells into cardiomyocytes and tissue engineering. Dr Hudson then completed postdoctoral training under the guidance of Prof Wolfram-Hubertus Zimmermann, one of the most prominent cardiac tissue engineering researchers. Dr Hudson returned to Australia in 2013 to work in the Cardiac Regeneration Lab in the School of Biomedical Sciences at The University of Queensland under Dr Enzo Porrello. In 2014 Dr Hudson became the co-head of the Cardiac Regeneration Lab with Dr Enzo Porrello and together they are working on finding novel therapeutics to facilitate cardiac regeneration.

Our laboratory is interested in understanding the molecular mechanisms that guide heart development and regeneration. We have recently discovered that the newborn heart has a remarkable capacity to regenerate itself following injury, which is in stark contrast to the adult heart. Our mission is to decipher the fundamental differences between the regenerative newborn heart and the non-regenerative adult heart. Ultimately, we hope to discover novel drug targets for the replenishment of heart muscle cells that are lost following a heart attack in order to allow the heart to heal itself and prevent heart failure. Our laboratory uses a variety of approaches including molecular genetic studies in mice through to functional genomic screens in human bioengineered heart muscle.