Profiles

Professor Alastair Stewart

 - Associate Investigator

Research focus: Mechanisms in inflammation and fibrosis in respiratory disease - mechanopharmacology in drug discovery and ultra-high content screening


Alastair Stewart is a Professor of Pharmacology, Co-Director of the Lung Health Research Centre and Director of the ARC Industrial Transformation Centre for Personalised Therapeutic Technologies at the University of Melbourne.  He has extensive experience in the field of respiratory and inflammation research. Alastair has published over 200 papers, had numerous patents proceed to grant and he has served on peer review committees for NHMRC and the scientific advisory boards of several Australian Medical Research Institutes.  His research interests focus on tissue remodelling and a quest for discovery and development of novel drugs targeting tissue remodelling and inflammation.  His long-term interest in steroid pharmacology has also encompassed several studies in tumour biology.  He is currently focussed on elucidating determinants of steroid sensitivity, particularly in airway structural cells and is leading translational research projects seeking novel treatments for steroid resistance. He is developing and applying the concept of mechanopharmacology in drug discovery and ultra-high content screening.  His laboratory has a strong track record of Graduate Research training and he maintains wide interests in education, research, research training and research support structures.  He has been extensively involved with meeting organisation throughout his career, having been a founding member of the International Young Investigators Smooth Muscle meeting series.  More recently he has chaired the Airway inflammation and remodelling (AIR) meetings in Melbourne in 2012 and 2014, 2016.   He is currently Vice President of the Asia Pacific Federation of Pharmacologists.  He promotes interdisciplinary research through roles on Editorial Boards including, Respiratory Research, Pharmacological Research Perspectives and Frontiers in Pharmacology (Translational Pharmacology).