Liyuan Wang

Hemaetopoiesis Dr Robert Nordon
PhD student at the University of New South Wales
Recipient of Graduate School of Biomedical Engineering postgraduate scholarship

Liyuan Wang is a third year PhD student studying at Graduate School of Biomedical Engineering, University of New South Wales.

Liyuan completed her Bachelor of Science at South-Central University for nationalities in China in 2008 majoring Biotechnology. Her thesis was on the effect of rice blast gene pi36 on the expression of disease related OsWRKY family. Together with Dr. Xinqiong Liu and others, a paper was published in 2010 in Chinese Science Bulletin. She then chose to study in School of Chemical Engineering with a major in Food Safety and Quality. Her 12 months project was on Vitamin B12 content in Australian Red Meat and Chicken using HPLC under the supervision of Dr. Jayashree Arcot. She was awarded Master of Science in 2011.

Liyuan applied for PhD in Graduate School of Biomedical Engineering later in 2011. She got the opportunity to join Dr. Robert Nordon’s research group. Her thesis is studying the angiogenic properties of endothelial cells in soluble and immobilised VEGF gradient. Currently, she is using microfluidic systems to establish gradient in vitro for live cell imaging, particularly focusing on the involvement of Rho GTPases that are key regulators of cytoskeleton in highly dynamic membrane protrusions.

The microfluidic devices are based on the diffusion of two different medium reservoirs, providing a steady growth factor gradient for cell migration study. She is interested in tracking cells using in-house semi-automated tracking software developed by Dr. Robert Nordon. Furthermore, Fluorescence Resonance Energy Transfer (FRET) probes were encoded by Raichu plasmids (constructed by Matsuda lab in Kyoto University), providing a tool to visualise spatio-temporal activities of Rho GTPases. Cloning work on plasmids has started to generate experiment control using standard molecular biology methods.Liyuan was awarded a Graduate School of Biomedical Engineering postgraduate scholarship in August 2013. With an interdisciplinary background, Liyuan might utilise her skills in stem cell lineage tracking research.
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