Olivia Stonehouse

Haematopoiesis Dr Samir Taoudi
PhD student at Walter and Eliza Hall Institute
Recipient of scholarship
After completing a successful honours degree at the University of Melbourne, I began my PhD focusing on the processes driving haematopoietic stem cell (HSC) emergence. 

Haematopoietic stem cells (HSCs) lie at the foundation of the haematopoietic system. HSCs have the unique ability to self-renew and seed all blood lineages, making them an attractive therapeutic tool for the treatment of blood-related diseases. Improving our understanding on the intrinsic and extrinsic mechanisms that regulate the stem and progenitor compartments, as well as methods for in vitro and in vivo stem cell manipulation, will be imperative for informing new therapeutics in regenerative medicine.
 
For this reason, my project investigates genes up-regulated during the maturation of pre-HSCs (precursor HSC) cell into HSCs. A knockout strategy has been employed to identify genes essential for HSC biology and assist in the development of better protocols for regenerative medicine. 

Contact student by stonehouse.o@wehi.edu.au