Lulu's image is of an adult mouse hippocampus, the area of the brain where new memories are formed. Astrocytes (green) were observed around the granule cell layer of the dentate gyrus, as indicated by cell nuclei (red). Some astrocytes were derived from neural precursor cell population (blue).
In her PhD studies, Lulu is assessing the contribution of stem cells in the brain following injury using an animal model of multiple sclerosis. She is particularly interested in exploring the contribution of two distinct populations of stem cells in the adult brain: neural precursor cells (NPCs) that are responsible for the generation of neurons and glia in the normal adult brain; and oligodendrocyte progenitor cells (OPCs) that are principally responsible for the generation of specialized glia called oligodendrocytes. Although OPCs have known to play an important role in remyelination for some time, recent evidence suggests that NPCs could also contribute to the generation of new oligodendrocytes after CNS damage. Lulu is supervised by Dr Toby Merson and Prof Trevor Kilpatrick
Lulu is supported by a Stem Cells Australia Strategic Australian Postgraduate Award.