UQ researchers develop new method to create stem cells for bone repair

01 March 2012
Researchers from Australian Institute for Bioengineering and Nanotechnology (AIBN) and UQ Clinical Research Centre (UQCCR) have developed a new method to create mesenchymal stem cells (MSCs). 

The new method will have the potential to one day replace the harvesting of bone marrow, presently conducted through highly-invasive procedures such as a lumbar puncture.
Researchers from 
AIBN Associate Professor Ernst Wolvetang said the new method has overcome a significant barrier in the translation of stem cell based therapy.
“We are very excited by this research, which has brought together stem cell researchers from two of the major UQ research hubs – UQCCR and AIBN,” A/Prof Wolvetang said.
The new method can use a small molecule to rapidly create MCSs using induced pluripotent stem (iPS) cells, which were artificially derived from skin cells.

The research is published in the February edition of the STEM CELLS Translational Medicine journal.

For more information:
Breakthrough in stem cell research 
Small Molecule Mesengenic Induction if Human Induced Pluripotent Stem Cells to Generate Mesenchymal Stem/Stromal Cells Stem Cells Translational Medicine (2012) Chen YS et al 1(2):83-95 (subscription maybe required)