Young researcher’s success recognised at international conferences

15 October 2018
Dr Thierry Jarde with supervisor A/ Prof Helen Abud and leader in organoids field, Prof Hans Clever.
Dr Thierry Jarde, Monash University, was awarded a significant Fellowship to attend the EMBO-EMBL Symposium in Heidelberg, Germany, as well as the opportunity to present his work to over 450 attendees at the Symposium.
The Symposium, “Organoids: Modelling Organ Development and Disease in 3D Culture”, brought together leading researchers in the organoid field, to enhance the understanding of how organoids can be used to study disease and how they might eventually be used to regenerate and replace human organ tissue.

Organoids, or mini-organs, are three-dimensional structures developed from stem cells. They mirror the specific organ tissues in a dish. The ability to grow human tissues in 3D organoid cultures has the potential to revolutionise the drug discovery process and regenerative medicine.

Thierry is a Senior Researcher in the Epithelial Regeneration Laboratory at Monash University, led by Associate Professor Helen Abud. His study was one of eight, from over 200 submitted, that was selected by the EMBO-EMBL Symposium’s organising committee to be presented at the Symposium. On the organising committee was Professor Hans Clever, who’s work started the organoid field, as well as internationally renowned kidney researcher, Professor Melissa Little. 

The study was completed in collaboration with Professor Jose Polo and Dr Christian Nefzger in the Polo Group at the Australian Regenerative Medicine Institute. The study used organoids to explore how aging impacts the stem cells that reside in the gut, which renew the gut lining every 3-5 days. 

The team also reprogrammed the stem cells from older mice to act like young stem cells; they had rejuvenated the stem cells in the dish. 

This study was the first of its kind and its success was possible through collaboration between groups. 

“Collaboration drives these projects forward; each person brings with them skills that complement the team” said Thierry. “I am very good at culturing and maintaining intestinal organoids in a dish. Christian has great reprogramming skills.” 

Thierry’s success as a researcher was also recognised at the Cambridge International Stem Cell Symposium, where he received an award for his presentation on a different project defining a key niche signal that supports intestinal stem cell proliferation. He was also selected to be a speaker at the International Society for Stem Cell Research (ISSCR) annual meeting and an Ambassador at the ISSCR public forum in June. 

Congratulations Thierry. 

Associate Professor Helen Abud and Professor Jose Polo are Chief Investigators at Stem Cells Australia.