Please join us for our monthly seminar series in the Seminar Room on Level 5 of the Melbourne Brain Centre
with drinks and nibbles to follow at 5pm.
Using embryonic stem cells to model human development
Professor Andrew Elefanty
Group Leader, Blood Cell Development & Disease, Murdoch Childrens Research Institute and Laboratory Head, Embryonic Stem Cell Differentiation Laboratory, Monash Immunology and Stem Cell Laboratories, Monash University
Andrew Elefanty trained as a physician in medical oncology and completed a PhD in leukemogenesis under the supervision of Prof Suzanne Cory at the Walter and Eliza Hall Institute of Medical Research. He subsequently developed an interest in the differentiation of embryonic stem cells as a model system to study early development. His work is focused on human ESC differentiation along mesodermal (blood, endothelium and heart) lineages.
The laboratories that he has headed along with long-term collaborator Prof Ed Stanley have made significant contributions to the culture of human ESC, and they have developed a robust system for human ESC differentiation. They have generated genetically modified human ESC lines in which fluorescent reporters have been introduced into key gene loci that allow objective monitoring of in vitro differentiation. A major goal of Prof Elefanty's work is to utilise ESC differentiation in order to understand human development, to generate tools for drug discovery, and eventually to provide a source of cells for therapy.