Top cardiac and vascular scientists come together

13 November 2017
Welcome to the 2017 Cardiac conference

The Australian Network of Cardiac and Vascular Developmental Biologists seeks to advance the disciplines of developmental and regeneration biology of the cardiac and vascular systems through leadership, good communication and education. 

The 2017 meeting, which ran on 2-3 November in Brisbane, brought together top cardiac and vascular scientists in Australia working in the developmental and regenerative biology space.  Multiple disciplines were covered, from tissue engineering, stem cell biology and differentiation, in vivo development, cell therapeutics, organ regeneration, disease modelling, and genomics.

Keynote addresses were given by James Martin and Elisabetta Dejana. Dr Martin began the conference outlining his work on the Hippo pathway, a key regulator of organ size, as a novel and effective approach for manipulating cell cycle activity in adult cardiomyocytes to stimulate cardiac regeneration.

Dr Dejana is an international expert in vascular biology and presented extensive data on her studies on the genes, signalling pathways, and cell physiological mechanisms underlying vascular development with a focus on the pathogenesis of cerebral cavernous malformations.

Cardiovascular disease continues to be the leading cause of death worldwide. Currently one in three die from cardiovascular disease each year. The lack of endogenous organ regeneration and repair mechanisms in the context of acute or chronic injury results in significant scar formation and dysfunction leading to heart failure. Recent studies in vascular and cardiac development and regeneration have provided new insights to address this significant public health burden.

Scientists continue to gain new understandings into the genetic, epigenetic, and signalling basis of cardiovascular development and disease and aim to leverage the power of model systems including mice, zebrafish, and stem cells to develop new therapies, model diseases through bioengineering, and advance developmental studies.

Interfacing with clinicians remains a key priority to understand how discoveries made at the bench translate to the clinic.

A total of 83 registered for the meeting representing academics from The University of Queensland, the University of South Australia, University of Sydney, the Victor Chang Cardiac Research Institute, Monash University, the Australian Regenerative Medicine Institute, the University of Melbourne, the Murdoch Children’s Research Institute, and the University of New South Wales.

This was a joint meeting of the Australian Network of Cardiac and Vascular Developmental Biologists and Stem Cells Australia.

Stem Cells Australia supported this meeting as the annual event of the Cardiac Theme.